Voluntary wheel running can lead to modulation of immune checkpoint molecule expression
نویسندگان
چکیده
منابع مشابه
Neuroprotective effects of voluntary wheel running and eriobotrya japonica flower extract on Parkinsonian rats
Backgrounds: The loss of dopamine-secreting cells and the decrease in the status of antioxidant is associated with incidents of Parkinson's disease. The purpose of the present study was to determine the protective effect of a 12- weeks voluntary wheel running (VWR) along with the injection of eriobotrya japonica flower extract (EJFE, 200 mg/kg body weight, 3 days a week) on cer...
متن کاملMEMRI Study of Mice Cerebellar Activation after Voluntary Wheel Running
INTRODUCTION: There is increasing interest in studying functional and cellular effects of environmental stimuli for better intervention in neurological rehabilitation [1, 2]. Recent studies have been using BOLD-fMRI to detect the neural activity in living animals [3] and human [4]. However it is technically difficult to apply BOLD-fMRI to nonrestrained animals due to its extreme susceptibility ...
متن کاملNeurobiology of Mice Selected for High Voluntary Wheel-running Activity.
Selective breeding of house mice has been used to study the evolution of locomotor behavior. Our model consists of 4 replicate lines selectively bred for high voluntary wheel running (High-Runner) and 4 bred randomly (Control). The major changes in High-Runner lines appear to have taken place in the brain rather than in capacities for exercise. Their neurobiological profile resembles features o...
متن کاملNeurobiology of Mice Selected for High Voluntary Wheel-running Activity1
SYNOPSIS. Selective breeding of house mice has been used to study the evolution of locomotor behavior. Our model consists of 4 replicate lines selectively bred for high voluntary wheel running (High-Runner) and 4 bred randomly (Control). The major changes in High-Runner lines appear to have taken place in the brain rather than in capacities for exercise. Their neurobiological profile resembles ...
متن کاملVoluntary wheel running attenuates lipopolysaccharide-induced liver inflammation in mice.
Sepsis induces an acute inflammatory response in the liver, which can lead to organ failure and death. Given the anti-inflammatory effects of exercise, we hypothesized that habitual physical activity could protect against acute sepsis-induced liver inflammation via mechanisms, including heat shock protein (HSP) 70/72. Male C57BL/6J mice (n = 80, ∼8 wk of age) engaged in physical activity via vo...
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ژورنال
عنوان ژورنال: Acta Oncologica
سال: 2020
ISSN: 0284-186X,1651-226X
DOI: 10.1080/0284186x.2020.1817550